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所属部门：

威尼斯9499登录入口

职务/职称：

讲师

电子邮件：

wql0143@nwu.edu.cn

个人简介

汉族，中共党员，硕士生导师。大连理工大学生物化工博士，香港高等研究院博士后。2020年11月加入威尼斯9499登录入口。主要开展食源性病毒感染及其靶向阻断机制研究；新型高效食品糖酶挖掘及结构功能研究；研究成果发表在国际高水平期刊PNAS、Nature Communication等期刊，欢迎各位同学加入。承担本科生《食品化学》、《生物化学》及研究生《食品生物技术》等授课课程。 

研究成果

科研项目：

01/2023-12/2025 国家自然科学基金青年项目 基于糖芯片技术的人源诺如病毒P蛋白与母乳寡糖互作及机制研究（主持）

07/2022-06/2024 中国科学院开放课题 母乳中抗诺如病毒有效糖蛋白成分鉴定及分析（主持）

01/2021-12/2022 陕西省教育厅项目  阻断诺如病毒的母乳糖链鉴定与分析（主持）

01/2021-12/2024 国家自然科学基金面上项目, B族肠道病毒受体筛选及入侵机制研究, （参与）

发表科研论文

(1) Qingling Wang#; Qian Yang#; Congcong Liu#; Guoqing Wang; Hao Song; Guijun Shang; Ruchao Peng; Xiao Qu; Sheng Liu; Yingzi Cui; Peiyi Wang; Wenbo Xu; Xin Zhao; Jianxun Qi; Mengsu Yang; George F. Gao*. Molecular basis of differential receptor usage for naturally occurring CD55-binding and-nonbinding coxsackievirus B3 strains, Proceedings of the National Academy of Sciences, 2022, 119 (4): e2118590119.

(2) Qingling Wang*; Jianli Guo; Lijia An; Yongming Bao*,Integration of DSF and Temperature Signals for RpfC/RpfG Two-Component System Modulating Protease Production in Stenotrophomonas maltophilia FF11, Current Microbiology, 2022, 79(2): 54.

(3) Ruchao Peng#;.Qingling Wang#; Jianxun Qi*; and George Fu Gao*; Cell entry by SARS-COV-2, Trends in Biochemical Sciences, 2021,1807(3).

(4) Zengyuan Zhang#;.Qingling Wang#, Yuqin Zhang; Liang Wang; Hanyi Liao; Anqi Zheng; Sufang Ma; Zheng Fan; Huifang Li; Weijin Huang; Yuhai Bi; Xin Zhao; Qihui Wang; George F. Gao*; Haixia Xiao*; Zhou Tong*; Jianxun Qi*; Yeping Sun*, The molecular basis for SARS-CoV-2 binding to dog ACE2, Nature Communication, 2021, 12:4195.

(5) Qingling Wang; Fangling Ji; Jianli Guo; Yuepeng Wang; Yanyan Li; Jingyun Wang; Lijia An; Yongming Bao, LotS/LotR/Clp, a novel signal pathway responding to temperature, modulating protease expression via c-di-GMP mediated manner in Stenotrophomonas maltophilia FF11, Microbiological Research, 2018, 214: 60-73.

(6) Qingling Wang; Fangling Ji; Jingyun Wang; Bo Jiang; Lu Li; Lijia An; Yachen Li; Yongming Bao, Characterization of a salt-activated protease with temperature-dependent secretion in Steno trophomonas maltophilia FF11 isolated from frozen Antarctic krill, Journal of Industrial Microbiology & Biotechnology, 2016, 43(6): 829-840

(7) Lifeng Fu#; Shuai Shao#; Yong Feng#; Fei Ye#; Xue Sun; Qingling Wang; Feng Yu; Qisheng Wang; Baoying Huang; Peihua Niu; Xuebing Li; Catherine C. L. Wong; Jianxun Qi; Wenjie Tan; George Fu Gao; Mechanism of Microbial Metabolite Leupeptin in the Treatment of COVID-19 by Traditional Chinese Medicine Herbs, Mbio, 2021, 12 (5): e02220-21.

(8) Shuang Song; Haoran Peng; Qingling Wang; Zhengqi Liu; Xiuping Dong; Chengrong Wen; Chunqing Ai; Yujiao Zhang; Zhongfu Wang; Beiwei Zhu*, Inhibitory activities of marine sulfated polysaccharides against SARS-CoV-2, Food Function, 2020, 11(9): 7415-7420.

[9] Jianli Guo, Qingling Wang, Yue Zhang, Wenhui Sun, Shuangzhe Zhang, Yachen Li, Yongming Bao*. Functional daidzein enhances the anticancer effect of topotecan and reverses

BCRP-mediated drug resistance in breast cancer. Pharmacol. Res. 2019, 147, 104387.

[10] Jianli Guo, Qin Tang, Qingling Wang, Wenhui Sun, Zhongji Pu, Jingyun Wang, Yongming Bao*. Pifithrin-αenhancing anticancer effect of topotecan on p53-expressing cancer cells. Eur. J. Pharm. Sci. 2018, 128, 61.

[11] 包永明#, 王庆玲#, 微生物学杂志, 2018, 38, 6.